In southern Africa, faith communities and religious institutions play a major role in assisting believers to find health, healing and well-being in everyday life. The Reformed tradition is often considered as neglecting these very matters. The study argues that this influential tradition has the resources to respond meaningfully to the needs of believers. The Reformed emphasis on the Holy Spirit is explored as one particular fruitful avenue to engage with healing. Issues of health, body and direct divine intervention are delicate themes in Reformed theology, but they represent also an intellectually challenging field of study. To utilise the potential of Reformed theology, the book investigates the complex and dynamic nature of health from a social constructivist approach. Four dominant patterns of health and healing are identified - the Ngoma paradigm, missionary medicine, the HIV/Aids discourse and the church-based healing tradition. As it turns out, each of these health discourses can be brought into dialogue with the Reformed understanding of the Holy Spirit. By offering a comprehensive contextual Reformed proposal on Spirit and healing the book makes a unique scholarly contribution. Themes such as relationality, transformation, quality of life and power are developed in a creative way in order to come to new perspectives on the Holy Spirit and healing.